Berens AJ, Cooper TL, and Lachance J (2017) The genomic health of ancient hominins. Human Biology (Accepted).



EvolutionLogo
Pagani L, Lawson D, Jagoda E, Mörseburg A, Eriksson A, … Lachance J (author 41 of 98), … and Metspalu M (2016) Genomic analyses inform on migration events during the peopling of Eurasia. Nature (.pdf ).



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Hsieh PH, Woerner AE, Wall JD, Lachance J, Tishkoff SA, Gutenkunst RN, and Hammer MF (2016) Model-based analyses of whole genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies. Genome Research 26:279-290 (.pdf).



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Hsieh PH, Veeramah K, Lachance J, Tishkoff SA, Wall JD, Hammer MF, and Gutenkunst RN (2016) Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection. Genome Research 26:291-300 (.pdf).



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Lachance J (2016) Hardy-Weinberg proportions and the mathematical population genetics of randomly mating populations. Encyclopedia of Evolutionary Biology, edited by Kliman RM. Academic Press. Vol. 2, pp. 208-211 (.pdf).



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Karmin M, Saag L, Vicente M, Wilson Sayres MA, … Lachance J (author 33 of 100), … and Kivisild T (2015) A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Genome Research 25:459-466 (.pdf).



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Lachance J and Tishkoff SA (2014) Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles. American Journal of Human Genetics 95:408-420 (.pdf).



AJHGlogo
Lachance J and Tishkoff SA (2013) Population genomics of human adaptation. Annual Review of Ecology, Evolution, and Systematics 44:123-143 (.pdf).



AREESlogo
Wang S, Lachance J, Tishkoff SA, Hey J, and Xing J (2013) Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from non-African populations. Genome Biology and Evolution 5:2075-2081 (.pdf).



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Lachance J, Jung L, and True JR (2013) Genetic background and GxE interactions modulate the penetrance of a naturally occurring wing defect in Drosophila melanogaster. G3: Genes Genomes Genetics 3:1893-1901 (.pdf).



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Lachance J and Tishkoff SA (2013) SNP ascertainment bias in population genetic analyses: Why it is important, and how to correct it. BioEssays 35:780-786 (.pdf).



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Johnson NA and Lachance J (2012) The genetics of sex chromosomes: evolution and implications for hybrid incompatibility. Annals of the New York Academy of Natural Sciences: The Year in Evolutionary Biology 1256:E1-E22 (.pdf).



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Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, Bodo JM, Lema G, Fu W, Nyambo TB, Rebbeck TR, Zhang K, Akey JM, and Tishkoff SA (2012) Evolutionary history and adaptation from high coverage whole-genome sequences of diverse African hunter-gatherers. Cell 150:457-46 (.pdf) .



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Pickrell J, Patterson N, Carbieri C, Berthold F, Gerlach L, Güldemann T, Kure B, Mpoloka SW, Nakagawa H, Nauman C, Lipson M, Loh PR, Lachance J, Mountain J, Bustamante C, Berger B, Tishkoff SA, Henn B, Stoneking M, Reich D, and Pakendorf B (2012) The genetic prehistory of southern Africa. Nature Communications doi:10.1038/ncomms2140 (.pdf).



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Lachance J, Johnson NA, and True JR (2011) The population genetics of X-autosome synthetic lethals and steriles. Genetics 189:1011-1027 (.pdf).



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Lachance J (2010) Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. BMC Medical Genomics 3:57 (.pdf).



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Lachance J and True JR (2010) X-autosome incompatibilities in Drosophila melanogaster: Tests of Haldane’s rule and geographic patterns within species. Evolution 64:3035-3046 (.pdf).



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Lachance J (2009) Inbreeding, pedigree size, and the most recent common ancestor of humanity. Journal of Theoretical Biology 261:238-247 (.pdf).



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Lachance J (2009) Detecting selection-induced departures from Hardy-Weinberg proportions. Genetics Selection Evolution 41:15 (.pdf).



GSElogo
Lachance J (2008) A fundamental relationship between genotype frequencies and fitnesses. Genetics 180:1087-93 (.pdf).



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Yukilevich R, Lachance J, Aoki F, and True JR (2008) Long-term adaptation of epistatic genetic networks. Evolution 62:2215-2235 (.pdf).



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Lachance J (2008) Subject to Change. Nature 454:916 (.pdf).



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