Genomics of human populations
Our lab uses whole genome sequencing to uncover human history and discover how genetic systems evolve. This includes detecting signatures of natural selection in the genomes of African hunter-gatherers, finding evidence of male-biased migration out-of-Africa, and inferring patterns of ancient and recent admixture. We are interested in evolutionary processes that result in large allele frequency differences across populations, such as bottlenecks and local adaptation. We use a hypothesis-driven approach to analyze genomic data, and an important theme of our research is the need to sequence individuals from a diverse set of global populations.